IMDiK - POST-DOC in the Laboratory of Immunology

Mossakowski Medical Research Institute

Polish Academy of Sciences in Warsaw

is looking for

a POST-DOC in the Laboratory of Immunology

Deadline for applications: 14^th January, 2024

Procedure ID: PI.110.4.2023

Expected starting date: February/March 2024

Institute website: www.imdik.pan.en

Laboratory website: https://imdik.pan.pl/en/laboratories/1312-laboratory-of-immunology

We are recruiting to the OPUS project No. 2023/49/B/NZ7/03915 entitled "Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficacy" funded by the National Science Centre and carried out at the Laboratory of Immunology at the Mossakowski Medical Research Institute Polish Academy of Sciences (MMRI PAS). The project is led by Dr. Małgorzata Firczuk. The Laboratory of Immunology is a new, rapidly developing scientific unit at MMRI PAS, bringing together young scientists and collaborating with numerous clinical and research teams in Poland and abroad. Currently, the Laboratory is implementing twelve projects funded by external agencies. We are looking for a candidate with a genuine passion for research, enthusiasm for discoveries, and a commitment to advancing scientific knowledge.

Information about the research project in which the candidate would participate:

Cell therapy using T cells modified with chimeric antigen receptors (CAR-T) is a novel and groundbreaking method for treating the most challenging cases of hematologic cancers, already applied in clinics, also in Poland. The project's goal is to identify new biomarkers for monitoring the effectiveness of CAR-T cell therapy. In particular, we will investigate proteases activated in CAR-T cells after their contact with tumor cells. In collaboration with the team led by Dr. Marcin Poręba from Wrocław University of Science and Technology, a partner in the project, we plan to develop probes enabling a precise assessment of protease activity using flow cytometry and mass cytometry. It is worth emphasizing that, while the project focuses on basic research to enhance our understanding of the mechanisms of CAR-T cell activation, the results obtained also carry translational and commercialization potential.

Description of duties:

planning and conducting experiments
creative work involving the analysis of current literature and initiating changes during project implementation
analysis and interpretation of acquired data
maintaining documentation of research results following FAIR principles
presenting results at seminars within the Laboratory and the Institute, as well as at broader scientific forums, including national and international scientific conferences
coordinating the work of students
writing scientific publications

Requirements for the candidate:

Ph.D. degree in biological/medical/pharmaceutical/chemical sciences or a related field
experience with laboratory work in the areas of biochemistry, molecular biology, experimental oncology, or immunology
scientific achievements documented by international publications in journals indexed in the JCR list
documented active participation in national and international conferences and symposiums
proficiency in spoken and written English
excellent organizational skills and attention to detail
ability to work independently and as a part of a team, strong communication skills

We offer:

a full-time employment contract for a period of up to 4 years
a salary of approximately 9000 PLN gross per month
innovative research challenges and unique opportunities for developing research skills
freedom and independence in carrying out assigned tasks
mentoring and support in professional career development
friendly, inspiring, and supportive work environment within the large team of the Laboratory of Immunology
opportunity to present research results at scientific conferences
support in publishing and promoting research findings
benefits package, including a Multisport Plus card and the option to participate in group insurance on preferential terms

Please submit the following documents:

motivation letter containing information about scientific interests, research work, and explaining why you want to work on the project
CV (signed by the candidate) in .pdf format
copy of the diploma confirming the academic degree
at least one letter of recommendation from the current or former supervisor/academic advisor

Apply via email to the project PI: Ten adres pocztowy jest chroniony przed spamowaniem. Aby go zobaczyć, konieczne jest włączenie w przeglądarce obsługi JavaScript., deadline for sending the application is 14^th January 2024. In the email title please include: „Post-doc” and procedure ID: PI.110.4.2023

Deadline for applications: 14^th January, 2024

Expected starting date: February/March 2024

Applications submitted after the deadline will not be considered. We reserve the right to invite only selected candidates for interviews.

INFORMATION CLAUSE ON PERSONAL DATA PROCESSING

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- MMRI PAS processes Your personal data in relation to a legal obligation (the Article 6.1.c of the GDPR) pursuant to Article 22¹§ 1 of the Act of 26 June 1974 Labour Code or Your consent understood by sending them to MMRI PAS (the Article 6.1.a of the GDPR) for data not listed on Labour Code, and their application does not affect the possibility of participating in the recruitment / competition. If you do not want us to process additional data, please do not include it in the documents.

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